DTT【3483-12-3】

Chinese alias: 1,4-dithiothreitol

English name: DTT

CAS :3483-12-3

Molecular formula: C4H10O2S2

Molecular weight: 154.25

Physical and chemical properties

Boiling point: 125～130°C

Specific gravity: 1.302

Storage: Very easy to oxidize, store in argon at 2-8℃

Sensitivity: sensitive to air, heat and humidity

Appearance: white crystal

Melting point: 42-43°C

Content: ≥99%

Packing: 1KG, 5KG, 25KG

Uses: Commonly used reducing agent, has antioxidant effect, participates in cell metabolism.

Compared with mercaptoethanol, DTT has similar effects, but the pungent odor of DTT is much smaller and the toxicity is much lower than that of mercaptoethanol. And when the concentration of DTT is 7 times lower than that of mercaptoethanol, the effects of the two are similar.

Used as protein sulfhydryl protective agent. Used for protein disulfide bond cleavage and sequence analysis. Sublimation at 37°C and 0.67Pa. Slight moisture absorption. Easily soluble in water, ethanol, acetone, ethyl acetate, chloroform and ether. Slowly oxidize in the air.